Relation between birth weight at term and growth rate, skeletal age, and cortical bone at 6-11 years

Author(s):  
Robert M. Malina ◽  
Peter T. Katzmarzyk ◽  
Gaston P. Beunen
Genetics ◽  
2000 ◽  
Vol 155 (3) ◽  
pp. 1369-1378 ◽  
Author(s):  
Grant A Walling ◽  
Peter M Visscher ◽  
Leif Andersson ◽  
Max F Rothschild ◽  
Lizhen Wang ◽  
...  

Abstract For many species several similar QTL mapping populations have been produced and analyzed independently. Joint analysis of such data could be used to increase power to detect QTL and evaluate population differences. In this study, data were collated on almost 3000 pigs from seven different F2 crosses between Western commercial breeds and either the European wild boar or the Chinese Meishan breed. Genotypes were available for 31 markers on chromosome 4 (on average 8.3 markers per population). Data from three traits common to all populations (birth weight, mean backfat depth at slaughter or end of test, and growth rate from birth to slaughter or end of test) were analyzed for individual populations and jointly. A QTL influencing birth weight was detected in one individual population and in the combined data, with no significant interaction of the QTL effect with population. A QTL affecting backfat that had a significantly greater effect in wild boar than in Meishan crosses was detected. Some evidence for a QTL affecting growth rate was detected in all populations, with no significant differences between populations. This study is the largest F2 QTL analysis achieved in a livestock species and demonstrates the potential of joint analysis.


1986 ◽  
Vol 7 (10) ◽  
pp. 299-304
Author(s):  
William P. Bunnell

Perthes disease is a condition of unknown etiology in which the vascular supply of the developing femoral head is temporarily interrupted, causing necrosis and collapse of the bony femoral head, followed by spontaneous revascularization and healing of the necrotic bone. It was independently described by four different authors (Legg, Calvé, Perthes, and Waldenstrom) in 1909 and 1910. They identified the condition as an affliction of the hip distinct from trauma and infection. The term "coxa plana" was applied to the characteristic flattening of the femoral head seen in Perthes disease. It was not until 10 years later that the actual pathology of avascular necrotic bone was described. EPIDEMIOLOGY The condition has its onset in children ranging in age from 2 to 12 years, with the majority of patients presenting between the ages of 4 and 8 years. Boys are affected four times more frequently than girls, and the condition is bilateral in approximately 15% of affected children. Certain constitutional factors are frequently found in children with Perthes disease. Skeletal age is delayed in nearly 90% of children affected with it. Affected boys have been found to be an average of 1 in shorter and affected girls 3 in shorter in height than their unaffected peers. Birth weight of affected children is frequently lower than average.


1988 ◽  
Vol 111 (2) ◽  
pp. 363-368 ◽  
Author(s):  
F. Ruvuna ◽  
T. C. Cartwright ◽  
H. Blackburn ◽  
M. Okeyo ◽  
S. Chema

SummaryData on gestation period of 701 indigenous East African and Galla does and pre- and postweaning growth of 810 pure-bred and cross-bred kids were analysed by least squares statistical analysis. Breeds of kids were East African, Galla, Toggenburg × East African, Toggenburg × Galla, Anglo-Nubian × East African and Anglo-Nubian × Galla. Average gestation length was 149 days and was significantly (P < 0·05) affected by type of birth of the kid, year–month of kidding, and age of dam. Does carrying twins had shorter gestation length than does carrying singles. Sex and breed of kid did not have significant effect on gestation length.Significant (P < 0·05) factors affecting birth weight, weight at 30, 60, 90, 120, 150, 210 and 270 days of age, and preweaning growth rate were breed and sex of kid, type of birth, year–month and age of dam. Male kids grew faster and were heavier than females. Kids born single were heavier and grew faster than twin-born kids. Kids from dams less than 3 years old weighed less than kids from older dams. Cross-bred kids had higher preweaning growth rates than indigenous pure-bred kids. The Anglo-Nubian × Galla cross was heaviest while the East African ranked lowest. The results point to importance of cross-breeding with temperate breeds to increase growth rates of indigenous goats. Comparison of Toggenburg and Anglo-Nubian sires for cross-breeding showed both buck breeds produced kids with roughly equal growth rates. Evaluation of indigenous Galla and East African dams for cross-breeding showed Galla dams produced heavier kids than East African but preweaning growth rates were not significantly different.


1978 ◽  
Vol 18 (90) ◽  
pp. 34 ◽  
Author(s):  
RA Hunter

Merino ewes were mated at pasture and then fed in pens either a maintenance or an 80 per cent maintenance ration of wheat grain three times a week. Half the animals at each feeding level were offered Spotted Gum (Eucalyptus maculata) sawdust. Addition of sawdust to the ration did not affect liveweight change and the wool growth rate of ewes or the birth weight and growth rate of lambs. It did, however, affect the long-term survival rate of ewes. Of the ewes that died after three months of survival feeding, four were in groups fed wheat alone and one in a group fed sawdust with the wheat. The survival rate and growth rate of lambs in all treatments were poor.


1992 ◽  
Vol 15 ◽  
pp. 183-184 ◽  
Author(s):  
L. Rydhmer

The birth weight of the piglet has an important influence on many aspects of later performance. There are, for example, relations between birth weight and growth rate as well as between birth weight and litter traits at farrowing (Rydhmer, Eliasson, Stern, Andersson and Einarsson, 1989). In a shorter perspective, birth weight affects piglet survival during the first weeks of life.High Utter size (number born) is a common breeding goal. Piglet weight is related to the number of piglets in the Utter. Piglet weight is also related to survival; thus mortality increases with litter size.The aim of this work was to study variation in piglet weight, some factors that may influence piglet weight and relations between litter size, piglet weight and piglet survival.Individual piglet weights were registered in 747 litters from an experimental farm. Of the 8134 piglets born, 2326 were Swedish Yorkshire, 239 Swedish Landrace, and the rest were crosses between these two breeds. One-third of the piglets were born in gilt litters. The piglets were creep fed from the 2nd week and weaned at 6 weeks of age. They were individually weighed at birth and at 3, 6 and 9 weeks of age. Birth weight in this report refers to the weight of all piglets born, including those stillborn.


1955 ◽  
Vol 6 (2) ◽  
pp. 308 ◽  
Author(s):  
PG Schinckel

Observations are reported on factors affecting the ratio of secondary to primary follicles (SJP) in a flock of Merino sheep.It was found that all follicles were initiated prior to birth but that the number which finally came to maturity (production of fibre) was significantly affected by birth weight and growth from birth to 1 month. Growth at later ages appeared to be unimportant. There was a significant correlation (r = +0.29) between birth weight and log potential S/P at birth. This is interpreted to indicate that while pre-natal growth conditions affect the number of follicles initiated, other factors are also of considerable importance. It is concluded that the larger animals at birth also have a greater total number of primary follicles than smaller animals. It is further concluded that this difference in total primary follicles results primarily from differences in size a t the 90th day of pre-natal life rather than from differences in density a t that time.


1974 ◽  
Vol 14 (69) ◽  
pp. 434 ◽  
Author(s):  
PA Kenney ◽  
IF Davis

A study of the survival and growth of lambs was made over a three year period (1968 to 1970) on a flock of 540 ewes grazing annual pasture at Werribee, Victoria. Ewes were stocked at three rates (5, 7 1/2 and 10 ha-1) and lambed between July 6 and August 20 or between September 10 and October 29 each year. Observations were made on the same ewes each year. Rate of stocking had no effect on the birth weight of lambs but single-birth lambs born in September were lighter than those born in July. More twins were born in September than in July and a smaller proportion of lambs born survived from the September than from the July lambing. Of the lambs born to ewes stocked at 10 ha-1 in 1968 and 1969 a smaller proportion survived than of the lambs born to ewes stocked at 5 ha-1. The growth rate of lambs born in July was constant between birth and weaning at 12 weeks of age but declined as rates of stocking increased. When the lambs born in September were about eight weeks old the pastures matured and growth rates of lambs declined and at weaning liveweights of lambs from plots stocked at different rates were similar. Lambs born in July on plots stocked at 5 and 79 ewes ha-1 were as much as eight kilograms heavier at weaning than the lambs born in September at equivalent rates of stocking. Neither rate nor time of onset of milk production was significantly affected by stocking rate.


1991 ◽  
Vol 31 (4) ◽  
pp. 455 ◽  
Author(s):  
GJ Sawyer ◽  
DJ Barker ◽  
RJ Morris

The preweaning growth of the progeny from 2531 first-calf heifers calving on commercial properties in the south-west of Western Australia was studied over 5 years. Animals included the progeny of Angus sires mated to Angus, Angus x Friesian, Simford, Hereford and Beef Shorthorn crossbred heifers; the progeny of Hereford sires mated to Hereford, Hereford x Friesian, and Beef Shorthorn crossbred; and those of Devon crossbred, Simford or Wokalup multibreed heifers mated inter se. Calves were born between mid January and July of each year and date of birth, calving information and calf growth through to weaning at an average age of 230 days were recorded. Data recorded on the calves' dams included regular liveweight and condition score assessment and the date of second calving. Angus-sired calves were lighter at birth than Hereford-sired calves; breed means ranged from 25.1 kg for purebred Angus to 33.2 kg for Wokalup multibreeds, with male calves weighing 1.4 kg more than females at birth. Calf birth weight was positively and linearly related to weight of dam at the beginning of joining. Breed of calf, sex of calf, year of birth, day of the year born, liveweight and liveweight change of the dam at the beginning of rejoining all significantly influenced calf growth, with up to 64% of variation accounted for. At 50 days of age, Devon crossbreds, Simfords and Wokalup multibreeds were significantly heavier than crossbred Hereford or Angus calves, and this trend persisted until weaning. The average growth rate to 200 days of Angus calves was 0.113 kg/day slower, and Hereford calves 0.77 kg/day slower, than the average growth rate of their respective crossbred calves. Heaviest 200-day weights were found in Devon crossbred (235 kg), Simford (221 kg) and Wokalup multibreed (219 kg) calves. A strong seasonal influence on calf growth was detected. Each 1 day increase in calf age in calves born between mid January and June resulted in 0.29 kg extra liveweight at 100 days and 0.68 kg extra liveweight at 200 days of age. Overall, the liveweight of the dam at the beginning of re-joining was positively associated with calf growth, with 0.119 kg of calf liveweight/kg dam liveweight at 100 days and 0.123 kg at 200 days. There was less effect of dam liveweight in Herefords and Hereford x Friesians on calf growth to 200 days, but this relationship was closer in faster growing and later maturing breeds, including Angus x Friesian, Simford, and Wokalup multibreed. The dairy crossbreeds generally lost weight at the beginning of re-joining, resulting in a negative association between this weight change and calf growth to 100 days. No assistance was required in 93% of calvings and the highest incidence of dystocia corresponded with the highest birth weight calves in Wokalup multibreeds. The most common calving difficulty was an apparently slow birth where no assistance was given, resulting in a stillborn calf. Male calves experienced 3 times the level of dystocia recorded for female calves. There was no association detected between dystocia and dam liveweight subsequent to calving. The study highlighted the importance of dam breed, liveweight and condition of the dam and timing of calving as important influences on the growth of progeny reared by first-calf heifers.


1986 ◽  
Vol 42 (2) ◽  
pp. 183-193 ◽  
Author(s):  
G. Simm ◽  
C. Smith ◽  
J. H. D. Prescott

ABSTRACTSelection indices to improve the efficiency of lean meat production in cattle were derived with an aggregate breeding value which comprised growth rate, food conversion efficiency, killing-out proportion and carcass lean proportion. Index measurements were growth rate, food conversion efficiency and ultrasonic fat area. Relative economic values of traits in the aggregate breeding value were calculated for an 18/20-month beef system, assuming a fixed national output of lean meat. Literature estimates of phenotypic and genetic parameters were used. Two indices were derived, one with a complete restriction on genetic changes in birth weight, and the other without restriction. Correlations between the index and the aggregate breeding value were 0·53 for the restricted index, and 0·57 for the unrestricted index. The maximum proportional reduction in expected economic response, due to complete restriction of birth weight was about 0·08. Selection on either index would actually lead to a slight decrease in carcass lean proportion, but this was less than the decrease expected from selection solely on growth rate. Correlations between the indices and the aggregate breeding value (measuring the accuracy of selection) fell by only about 0·01 when ultrasonic measurements were omitted from the index, but fell by about 0·09 when food conversion efficiency was omitted. Sensitivity of the indices to changes in parameters was also examined. With proportional changes of ±0·5 in individual economic weights, or absolute changes of ±0·2 in genetic correlations or −0·2 in heritabilities, the efficiency of selection ranged from 0·93 to 1·00.


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